More than 80% of the respondents have been exposed to information. Consumers Association suggested strengthening corporate supervision.

  China Net Finance August 29th Today, China Consumers Association released an investigation report on the disclosure of personal information of App. In order to more accurately grasp the content scope, possible ways, problem forms, rights protection willingness and other relevant information of consumers’ personal information disclosure, and better safeguard consumers’ legitimate rights and interests, China Consumers Association organized a questionnaire survey on "App Personal Information Disclosure" from July 17 to August 13, 2018. The survey was conducted online, and a total of 5,458 valid questionnaires were collected.

  I. Main findings of the survey

  (1) Over 80% of the respondents have experienced personal information disclosure.

  According to the survey results, the overall situation of personal information disclosure is relatively serious, with 85.2% of people having experienced personal information disclosure and 14.8% not having experienced personal information disclosure.

  Figure 1: Have you ever encountered personal information disclosure?

  (2) Common problems encountered after personal information is leaked: harassing sales calls or text messages, receiving fraudulent calls, and receiving spam.

  According to the survey results, when consumers’ personal information was leaked, about 86.5% of the respondents were harassed by sales calls or text messages, about 75.0% of the respondents received fraudulent calls, and about 63.4% of the respondents received spam, ranking the top three. In addition, some interviewees have received illegal information such as illegal links, and even more, personal account passwords have been stolen.

  Figure 2: Expression of Personal Information Disclosure

  (C) Two key concerns of consumers’ personal information: being used for fraud and theft, and selling or exchanging it to a third party.

  According to the survey results, if the mobile App leads to the disclosure of personal information, the most worrying issue is being used for fraud and theft, accounting for 70.5%. Followed by selling or exchanging to a third party, accounting for 52.4%, being harassed by promoted advertisements accounting for 37.7%, and reputation damage accounting for 6.6%.

  Figure 3: Concerns about personal information disclosure

  (D) Operators’ unauthorized collection of personal information and intentional disclosure of information are the main ways of personal information disclosure.

  According to the survey results, the main way of personal information leakage is that the operator collects personal information without his consent, accounting for about 62.2% of the total sample of the survey; Second, operators or criminals intentionally disclose, sell or illegally provide personal information to others, accounting for about 60.6% of the total sample of the survey, and 57.4% of personal information is leaked due to loopholes in the network service system. There are also criminals stealing and defrauding personal information through Trojan horses and phishing websites, and operators collecting unnecessary personal information, accounting for 34.4% and 26.2% respectively.

  Figure 4: Ways of Personal Information Disclosure

  (5) About one-third of the respondents chose to admit that they were unlucky after the disclosure of personal information.

  According to the survey results, after personal information is leaked, respondents will take various measures to safeguard their rights and interests, such as complaining to consumer associations and relevant administrative departments, and some respondents will choose to negotiate with service providers and give feedback to relevant industry organizations.

  It is noteworthy that in the end, about one-third of the respondents chose to "admit that they are unlucky", which may be based on their inability to cope, on the other hand, they may accept the status quo after failing to cope.

  Figure 5: Measures taken after personal information is leaked.

  (6) Reading the APPlication authority and user agreement or privacy policy when installing and using the mobile app.

  1. In terms of reading habits, the respondents who choose "occasional reading" are the most.

  According to the survey results, when users install and use mobile apps, few people read the application rights and user agreements or privacy policies, and most of them read occasionally and never read. Always reading accounts for 18.1%, often reading 8.2%, sometimes reading 16.4%, occasionally reading 31.2% and never reading 26.2%.

  Figure 6: Habits of reading application permissions and user agreements or privacy policies.

  2. From the reading level, the respondents who chose "probably reading" were the most.

  According to the survey results, among 73.8% of the respondents who have read the application rights and user agreements or privacy policies, only 26.7% of the respondents can carefully read the written descriptions of the application rights and user agreements or privacy policies, less than 30%; Nearly 40% of the respondents will probably read the relevant policies, accounting for the highest proportion; About 20.0% of the respondents will choose to read the key chapters; Some respondents will occasionally check the application rights and user agreement or privacy policy text during the use process.

  Figure 7: The extent of reading application permissions and user agreements or privacy policies.

  3. "You can’t use it without authorization" is the main reason why respondents "never read".

  According to the survey results, among the 26.2% respondents who never read the application rights and user agreements or privacy policies, the main reason for choosing never to read them is that they can’t use them without authorization, and they can only be forced to accept them, accounting for 61.2%. There are also 22.2% of the respondents who trust the App operators, and 16.6% of the respondents think that the contents of the App user agreement are similar.

  Figure 8: Reasons for never reading application rights and user agreement/privacy policy.

  (7) More than 60% of the respondents take measures to fill in some personal information to protect the safety of personal information.

  According to the survey results, respondents mainly protect personal information security by filling in only a part of personal information when using App, accounting for 67.2%. 32.7% chose to turn off personalized services (such as location), 29.5% refused access to software, 24.6% installed relevant protection software, 18.0% used some false information during registration, and 4.9% of the respondents said they didn’t care.

  Figure 9: Personal Information Protection Measures

  (8) The permissions required by App are mainly to obtain location information and access contacts.

  According to the survey results, the right to read location information and the right to access contacts are the most frequently encountered when installing and using mobile apps, accounting for 86.8% and 62.3% respectively. The proportion of respondents who were asked to read the phone records (47.5%), read the short message records (39.3%), turn on the camera (39.3%) and record the microphone (24.6%) was relatively high.

  Figure 10: Permission required to install and use mobile APP.

  (9) Nearly 70% of the respondents believe that mobile apps gain user privacy rights when their functions are unnecessary.

  According to the survey results, it is more serious for mobile apps to obtain users’ privacy rights when their own functions are unnecessary. 67.2% of the respondents encountered this situation, and only 32.8% of the respondents did not.

  Figure 11: Do you get user privacy rights when using the mobile APP without its own functions?

  (10) Nearly 80% of the respondents believe that the reason why mobile apps collect personal information is to promote advertisements.

  According to the survey results, respondents believe that promoting advertisements is the most important reason for mobile apps to collect personal information, accounting for 77.0%. Other reasons were selling and exchanging personal information (45.9%), digging up users’ habits and providing better services (42.6%) and fraud and theft (24.6%).

  Figure 12: Why the mobile App collects personal information.

  (11) The main reasons for personal information security problems in mobile App are weak personal safety awareness and inadequate supervision.

  According to the survey results, weak awareness of personal information security protection and inadequate supervision are the main reasons why respondents believe that personal information security problems occur in mobile apps, accounting for 64.0% and 57.3% respectively. Imperfect relevant laws (39.3%), difficulty in obtaining evidence, high cost of rights protection (24.6%), weak awareness of rights protection (19.6%) and lack of self-discipline in the industry (18.0%) are also important reasons for personal information security problems in mobile apps.

  Figure 13: Reasons for Personal Safety Problems in Mobile APP

  (12) More than 80% of the respondents believe that the current mobile App needs to be strengthened in the protection of users’ personal information.

  According to the survey results, respondents believe that the current mobile App needs to be strengthened in terms of users’ personal information, with 62.3% of respondents thinking it is very necessary and 23.0% necessary, accounting for more than 80% of the total sample of the survey. The proportion of people who think it is unnecessary, unnecessary and completely unnecessary is relatively small.

  Figure 14: The willingness to strengthen the protection of users’ personal information in the current mobile App.

  1. Personal information disclosure is quite serious, and there are various ways and forms of information disclosure. According to the statistical results, the main ways of personal information leakage of consumers are that operators secretly collect personal information without their consent, operators or lawless elements deliberately disclose, sell or illegally provide personal information to others, and there are loopholes in the network service system, resulting in personal information leakage; When consumers’ personal privacy information is leaked, the most common situations are receiving fraudulent calls, sales calls, SMS harassment, spam and so on.

  2. Over-collection of personal information by mobile apps shows a general trend. According to the survey results, there are many kinds of permissions that mobile apps need to obtain, the most prominent of which is to obtain location information and access contact rights; Moreover, the user’s privacy rights are obtained when the function of the App itself is not necessary, which increases the risk of personal information disclosure; Most respondents believe that the reason why mobile apps collect personal information is to promote advertisements.

  3. The frequency and depth of consumers’ reading of mobile App application rights and user agreements or privacy policies need to be improved. According to the survey, more consumers never or occasionally read the text descriptions such as the application rights of mobile App and the user agreement or privacy policy. Moreover, due to the lack of knowledge of network technology and the length of written expression, some consumers will not fully read the written description of privacy policy, or browse it roughly, or read key chapters, and they are not deeply aware of it, and it is easy to miss key information or key descriptions. There are also a large number of consumers who can’t use the App without authorization and have never read the application rights and user agreement or privacy policy of the app.

  4. The countermeasures after the disclosure of consumers’ personal information are insufficient. According to the survey data, after the disclosure of personal information, consumers are most worried about being used for fraud and theft or handing it over to a third party; However, it is worth noting that there are not a few respondents who choose to respond negatively and feel unlucky, and consumers’ awareness of active rights protection needs to be strengthened.

  5. Consumers have a strong awareness of personal information security but lack effective protection means. The survey shows that users protect personal information security by filling in some information, and the weak awareness of personal safety and inadequate supervision are the main reasons for personal information security problems in mobile apps. On the one hand, consumers and mobile App service providers are often in an unequal position, and they can only agree or be forced to agree to format terms and information access rights; On the other hand, although consumers have a sense of self-protection, they don’t know how to protect themselves more effectively, and it is difficult to deal with them effectively.

  Iii. suggestions

  This survey shows that with the rapid development of the mobile Internet, the leakage of consumers’ personal information is not optimistic, and there is a general trend of over-collection of personal information by mobile apps. Consumers have many concerns, but they often lack sufficient effective countermeasures to protect consumers’ personal information and privacy. How to protect consumers’ personal information and privacy, respect consumers’ values and wishes, and make consumers’ personal information and privacy data no longer "streaking" and be reasonably respected and protected is inseparable from the extensive participation and common governance of all sectors of society. To this end, the China Consumers Association suggests:

  1. Improve relevant laws and regulations to provide a solid foundation for the long-term development of the industry. At present, China has issued some normative documents and recommended standards to regulate and guide the collection of personal information by App, but the disciplinary measures and compensation issues that consumers are generally concerned about are not deep enough. It is suggested to further clarify the rights and obligations of both parties in the network information service, especially the obligations and responsibilities of App service providers, do a good job in coping with and judging the risks and problems related to the application of personal information and data, and let the data industry in the network era develop within the scope of the rule of law.

  2. Strengthen the dynamic supervision of enterprises to provide a solid guarantee for the orderly development of the industry. The supervision of mobile App and the protection of personal information need the cooperation and dynamic supervision of the relevant departments such as industrial credit, market supervision, public security, culture and network security. First, strict access threshold and registration and filing, such as the review of developer qualifications, the registration and filing of App, the review of App service functions and contents, and all aspects of violation punishment mechanism should form a linkage to strengthen source governance; Second, severely punish all kinds of violations of laws and regulations, severely crack down on the black industrial chain of personal information trafficking, and form a normalized supervision mechanism for violations of consumers’ personal privacy information; The third is to pay close attention to the development trend of App in the market, such as jointly establishing an App spot check system and a blacklist system, and promptly publicizing the blacklisted software to remind consumers to download it carefully.

  3. Urge enterprises to be self-disciplined and provide internal motivation for the healthy development of the industry. First of all, App service providers must establish the awareness of the first person responsible for consumer rights protection, adhere to the "safety" bottom line, and strengthen the responsibility to protect consumers’ personal information; Secondly, enterprises should obtain user data in a reasonable and legal way, and take effective measures to ensure the safety of users’ personal information and data, and win consumers’ choice and trust with service quality and security guarantee; Third, enterprises should avoid misunderstanding and misreading by consumers in a concise, eye-catching and easy-to-understand way when providing relevant services and fulfilling their obligation to inform; Fourth, enterprises should fully listen to and respect consumers’ reasonable demands and opinions and give timely feedback to improve consumers’ satisfaction and trust.

  4. Encourage the public to participate and strengthen the popularization of network knowledge and safety education norms. On the one hand, it is necessary to widely mobilize social forces to jointly deal with the information leakage of mobile App through social propaganda, social mobilization, social participation and social supervision, strengthen the popularization of network knowledge and safety education norms, and enhance consumers’ awareness of personal information security protection and rights protection; On the other hand, it is necessary to unblock complaint channels and rights protection channels, and let consumers actively participate in the actions to safeguard personal information security through the construction of convenient complaint, report, feedback and handling channels, so as to enhance consumers’ rights protection will and effect.

  5. Cultivate good information credit awareness and usage habits. Consumers should pay attention to "four attentions" when choosing to use mobile App: First, they should pay attention to choosing safe and compliant App products and services, and choose formal and effective channels for download and installation; Second, we should pay attention to carefully reading the Application authority and user agreement or privacy policy description of the app to understand the operational precautions; Third, we should pay attention to cultivate good habits, do not arbitrarily open and agree to unnecessary reading rights, do not arbitrarily input personal privacy information, and regularly maintain and clean up relevant data; Fourth, we should pay attention to seriously deal with the problem of personal privacy information being leaked. When personal information is found to be leaked, we should take the initiative to protect rights in time through effective means and report it to relevant departments when necessary, so as to protect more consumers from it.

In this field, the United States is still far ahead.

 

Text: the sound of trees and grass in the forest

 

Proofreading: Chao Gan/Editor: Guo Licheng

 

Houston, an American city no stranger to China, is well-known for its rocket team and space city. People are deeply impressed by its developed petrochemical industry, staggered pipelines and busy factory ports.

 

There are more than rockets and oil behind Houston’s prosperity.

 

(Photo: shutterstock)▼

 

 

But to say that Houston’s most prosperous industry, it has to be the following:

 

The annual output value is as high as $14 billion, more than 90,000 people go to work, and many top medical institutions and researchers gather. By the way, one of the largest medical complexes in the world supports a quarter of Houston’s hotel business.Dezhou medical center.

 

Texas Medical Center "supported" a city on its own.

 

(Photo: Yitu. com) ▼

 

 

This achievement of Texas Medical Center was not achieved overnight, but was a leader in the industrial transformation of the United States for decades. Due to the large number of well-known hospitals gathered here, the supporting medical equipment, industry exhibitions, health consultation and other industries have also developed.

 

Compared with today’s depressed Great Lakes rust belt, Houston is still full of vitality.

 

Industrial explosion in the aging era

 

Houston’s success in the pharmaceutical industry, on the one hand, benefits from the strong strength of universities, scientific research and talents, but as an industry, the most fundamental reason for its rise is stillFundamental transformation of social population structure.

 

76 million people were born in the "baby boom" in the United States from 1945 to 1964, and the average age of the American population has been rising since then. Despite the continuous immigration supplement, compared with the obviously increased elderly population, the incidence of a series of diseases such as diabetes, cancer and Alzheimer’s disease is bound to increase, and the pharmaceutical market is bound to expand.

 

The baby boomers are getting old.

 

Directly raised the average age of the American population ▼

 

 

Aging is not exclusive to Europe and America.With the inevitable trend of economic development and fertility decline, China is no exception.. Moreover, China people’s awareness and demand for health are also obviously improving, which can be seen from the financial market: in the past 20 years, the pharmaceutical and biological industries have increased sevenfold, ranking among the top five in all industries; The scale of biomedical ETF(512290) is also rising step by step.

 

The pharmaceutical and biological industries are growing rapidly ▼

 

 

Biomedical ETF▼

 

 

In the age of aging, diabetes and obesity have become a problem that almost everyone has to face. At present, there are about 537 million people with diabetes in the world aged 20-79. Nowadays, the sale of all kinds of sugar-free drinks and foods on the market is a manifestation of people’s worries.

 

The treatment of diabetes, a chronic disease, is a worldwide problem. Otherwise, there will be no so-called "ancestral secret recipes" flying all over the sky. However,The emergence of GLP-1 drugs will be a blessing for patients..

 

GLP-1 (human glucagon-like peptide -1) is a protein secreted by human intestinal cells, which can promote human insulin secretion. However, GLP-1 secreted by human body is easy to be decomposed by other enzymes, and will not act for a long time. Then, if we improve the structure of GLP-1 so that it is not easy to be decomposed, won’t it promote insulin secretion for a long time and treat diabetes?

 

 

 

Science magazine listed the related research of GLP-1 as the top ten scientific breakthroughs in 2023.Among them, the most famous drug is undoubtedly Smegliptide, which has occupied half of the field of diabetes..

 

(Note: At present, this drug is only approved for the treatment of diabetes in China, but it has not been approved for weight loss! )

 

Smegliptide also shows great potential in the prevention and treatment of Alzheimer’s disease, nonalcoholic hepatitis, cancer and kidney disease, and it is quite aspirin-like "cure all diseases". In October last year, after Novo Nordisk announced the "positive experimental results" of smegliptide in the treatment of diabetic nephropathy, the share prices of many dialysis manufacturers fell. And this story has happened many times in the medical field.

 

The announcement shows that the efficacy of smegliptide has reached the expectation.

 

Therefore, the experiment was terminated early ▼

 

 

Lilly, a pharmaceutical giant, was originally a small company, but relied on its keen sense of smell to take the lead in obtaining insulin patents and monopolize the global market. However, in the 1980s, Novo Nordisk insulin injection pen went on the market, and this convenient and easy-to-use product sold well when it went on the market, which opened the era of hegemony in the diabetes drug market.

 

All these remind people that technology is constantly reshaping this market.An innovative achievement may create a new giant.; Another case is the wave caused by the listing of oral version of smegliptide in China in early 2024.

 

The oral version is also only approved for diabetes treatment.

 

Not approved for general weight loss!

 

(Photo: National Medical Products Administration) ▼

 

 

Massive capital investment and endless new achievements have created a vibrant biomedical industry today. In the past few decades, China, the fastest growing economy in the world, actually has a long-term shortcoming in the biomedical industry.Can you make up this short board?

 

China medicine, difficult to move forward.

 

Taking medicine when you are sick is something that everyone has to experience. However, the expensive drug price has become a pain in patients’ hearts. The dilemma in Dying to Survive may happen to each of us.

 

The reason why the drug price is so high is related to the current high cost of drug research and development:10 years, 1 billion dollars. For a long time, the pharmaceutical industry has been dominated by a group of large multinational pharmaceutical companies. On the one hand, it has high research and development costs and technical barriers. On the other hand, monopoly status means strong pricing power. Such a market situation has created amazing profit margins for large pharmaceutical companies: in 2023, the annual sales of smeagoutide reached $21.142 billion.

 

Novo Nordisk Meglumine Peptide Related Products Financial Report ▼

 

 

The pharmaceutical industry in New China originated from the eldest son of the Republic medicine-Shijiazhuang Huabei Pharmaceutical FactoryThe first batch of domestic penicillin in China was born here. However, due to our late start and weak foundation, we have never had any industrial advantages except for traditional Chinese medicine products with local characteristics for a long time. When foreign pharmaceutical companies with strong R&D strength and mature business model enter China, they are like wolves in the flock. If they don’t catch up, the pharmaceutical market of more than one billion people will be completely lost.

 

Chinese medicine is a symbol of moderns in Shijiazhuang ▼

 

 

At that time, China’s R&D ability was very weak, so we could only start with the production of basic raw materials for drugs. The ingredients of the raw materials are fixed, and the production process is relatively mature. As long as you are willing to do it, you can produce products. But the middle and lower reaches of this international industrial chain can receive a large number of orders only because of low labor costs. Moreover, the technological level was limited at that time, and the pollution in the production process was very serious.

 

This is obviously not a long-term solution. The vast market of all kinds of new drugs attracts China enterprises. Since they can’t make high profits in developing new drugs, let’s start with generic drugs and get a slice of the huge market first. Nowadays, many backbone enterprises in the pharmaceutical industry in China (such asHengrui Pharma, the heavyweight stock of biomedical ETF), it is in these two waves that the initial accumulation has been completed and it has moved to the upper reaches of the industrial chain.

 

From generic drugs to self-developed drugs

 

Enterprises need a certain amount of time to accumulate and precipitate.

 

(Photo: Picture Worm Creativity) ▼

 

 

At this time, the pharmaceutical industry in China has made great progress. But after all, I still follow in the footsteps of others, and I only earn a fraction of the big international pharmaceutical companies. If you really want to gain a foothold in the biomedical industry, you need to come up with your own things and change the old thinking and industrial model as a whole.Only by thoroughly remoulding oneself can we really grow up.

 

It is not only an economic and commercial issue to enlarge the local pharmaceutical industry. Even in the era of high globalization, the regional differences of health problems in different countries need the developed biomedical industry in their own countries.

 

For example, the Texas Medical Center mentioned at the beginning

 

Has the largest cancer center in the United States

 

(Photo: MD Anderson)▼

 

 

For example, due to the differences of environment and living habits in different countries, the incidence of cancer, the big health killer in the aging era, is different in different countries. The incidence of lung cancer and nasopharyngeal carcinoma in China is obviously higher than that in Europe and America, and esophageal cancer patients account for half of the world. Only by establishing an independent biomedical industry system can we better provide targeted treatment for patients.

 

Make your own medicine

 

Cancer, in most people’s minds, is equated with terminal illness. But the progress of modern medicine is enough to make this an old yellow calendar.

 

One of the major difficulties in cancer treatment is that cancer tissue has a strong ability to deceive, and it will "hide" itself under the guise of the identification mechanism in the human immune system to prevent cannibalism. In other words, if drugs can be used to "remind" the immune system and "catch the mole", it can play a role in preventing and treating cancer.

 

"There is a mole, terminate the transaction."

 

(T cells surround identified cancer cells)

 

(Photo: NICHD/J. Lippincott-Schwartz)▼

 

 

Research in this field has been carried out for decades, among whichPD-1/PD-L1 has attracted much attention from scientists.. Cancer cells will suppress T cells through this in vivo inhibitor, making it think it is a "friendly army". Scientists have developed drugs to block the inhibitory signal pathway between T cells and tumor cells, so as to "restart" the human anti-cancer mechanism.

 

Microscopically, PD-L1 positive lung adenocarcinoma cells

 

(Photo: wiki)▼

 

 

Such drug development requires high technology and in-depth study of human immune system. In the past, it was estimated that multinational pharmaceutical companies developed and sold high prices, and then domestic pharmaceutical companies waited for the patent period to pass a wave of imitation. However, times have changed.

 

By the end of 2023, 17 PD-(L)1 products have been approved for listing in China market, of which more than half are domestic products. In addition to PD-1 target, drugs such as PARP and CDK4/6 have also been successfully developed. Hengrui Pharma is one of the most important manufacturers in this field in China. Its biopharmaceutical products cover lung cancer, nasopharyngeal carcinoma and other high-risk cancer categories in China, and a large number of drugs are in the clinical research stage.

 

Some cancer-related drugs in Hengrui Pharma.

 

(Photo: Hengrui Pharma) ▼

 

 

But at present, the human response rate of PD-(L)1 drug is not high enough, and scientists are still improving it.

 

Since antibodies can recognize tumor tissues, people naturally think: Can you directly use it with chemical drugs to accurately find cancer cells and give him a "total annihilation"? After all, no matter how hard you work, you are afraid of a kitchen knife: no matter how tough a cancer cell meets a high dose of chemical drugs, it will only disappear.

 

Schematic diagram of the action mechanism of antibody-coupled drugs

 

(photo: ADCREVIEW)▼

 

 

This is antibody-based coupled drugs (ADC), which is one of the main anticancer drugs at present.. The principle is simple, but there are many difficulties in research and development: how do protein primers connect with "toxins" that attack cancer cells? How to ensure that you don’t play your medicine too early on the way to the "enemy camp"? How to "exit" in case of entering normal cells of human body? As a result, ADC drugs with complex structures have become research and development black holes. Once the research and development fails, it is difficult to find out which link has a moth.

 

How to design the parts of antibody conjugates

 

It is a big problem to maximize the drug effect ▼

 

 

In the past, this was the natural technical moat of large multinational pharmaceutical companies, which could greatly increase the price of drugs; But now, this is still the stage for China pharmaceutical companies to show their fists:At the end of 2023, BL-B01D1, an ADC dual-antibody drug for lung cancer and breast cancer, was developed by Bailey Tianheng, which set a record for China drugs to go to sea. Successfully went to sea with a down payment of $800 million and a potential price of $8.4 billion..

 

China’s biomedical industry has not only quickly caught up with the world-class phalanx, but also achieved a leading position in some fields.

 

Bai Li Tian Heng represents China Biomedical Haoheng.

 

(Photo: Bai Li Tian Heng) ▼

 

 

Both PD-1 and ADC use drugs to enhance the immune cell ability of human body or kill cancer cells. Then, directly enhancing the recognition ability of human immune cells can also achieve anti-cancer effect? It sounds like science fiction, but it has been realized in reality: using genetic engineering technology to inject receptor genes that can recognize the corresponding tumor cell antigens into immune T cells, so that they can accurately identify cancer cells. This is the CAR-T cell therapy technology.

 

Process diagram of CAR-T cell therapy technology

 

(Photo: MUSC)▼

 

 

At present, CAR-T is mainly used for the treatment of hematological cancers, including well-known leukemia. There are only ten models on the market in the world, and China has four models, including Regiosai injection of Wuxi PharmaTech, which is heavily held by biomedical ETF. In addition to the treatments already on the market,There are hundreds of CAR-T therapies being developed in China, the largest number in the world..

 

China’s bio-pharmaceutical industry, which once could only follow the big international pharmaceutical companies, has finally grown up.

 

Reggiorense injection is the second CAR-T product approved in China.

 

It is also the first CAR-T product of Class 1 biological products in China.

 

(Photo: Wuxi PharmaTech) ▼

 

 

The overall progress of this industry is inseparable from the joint efforts of this huge industrial chain. The listing of any drug requires sufficient clinical trial evidence and approval of relevant departments. For a long time, the approval speed of new drugs and new medical devices in China is slow, and a large number of drugs to be approved often pile up. In the high-speed development of drug research and development track, any time delay will miss business opportunities.

 

Since August 2015, the State Council issued the Opinions of the State Council on Reforming the Examination and Approval System of Medicines and Medical Devices, and a series of reform measures have been introduced one after another. In 2019, the newly revised Drug Administration Law established the MAH system for listed licensors, which mobilized the enthusiasm of more new drug research and development. The response of the market and industry is also extremely rapid, and various breakthroughs of biomedical enterprises in China have emerged in succession.

 

The core of MAH system is to separate drug marketing license from drug production license.

 

Allow pharmaceutical production enterprises, R&D institutions or researchers.

 

Become an independent drug marketing license holder

 

(Photo: Drug Administration Law) ▼

 

 

Go out to sea and look to the future.

 

The breakthrough in the related fields of innovative cancer drugs is only one aspect of the rapid progress of the biomedical industry in China. With the deepening of people’s cognition, medicine is more than just taking medicine to see a doctor; The future medicine will be a whole from genes to society. The biomedical industry in China is also making all-round progress.

 

Biomedicine in China is making efforts.

 

(Photo: Yitu. com) ▼

 

 

Since the 21st century, people have made many breakthroughs in cancer treatment. But no matter how to treat it, it is a process of suffering for patients. It would be best if it could be prevented.

 

At present, the human papillomavirus vaccine (HPV) is the only vaccine that has an obvious preventive and therapeutic effect on cancer (cervical cancer). Originally, it was expensive and all of it relied on imports. Many cities were in short supply and even went to Hong Kong to fight. nowDomestic bivalent HPV vaccine has been put on the market, and the cost of vaccination has been greatly reduced..

 

Bivalent HPV vaccine independently developed and produced by watson biological.

 

A needle costs less than 400 yuan.

 

(Photo: released by Kunming) ▼

 

 

People’s recognition of domestic vaccines is real.Zhifei Bio and watson biological held by Biomedical ETF.They all rely on relevant vaccine products to achieve good results in the capital market. It can be expected that this market will continue to grow after the domestic nine-valent vaccine is listed around 2025.

 

 

 

 

Under the constant technical update,The pharmaceutical industry will continue to reshuffle and opportunities will continue to emerge..

 

An unprecedented wave of aging has arrived, and the biomedical industry with long-term sustainable development potential is undoubtedly the biggest outlet under this trend. Houston Medical City has proved to us that this industry has unlimited potential and long-term stability, and it is also a great opportunity for the city to realize industrial transformation. For individual investors, this is a win-win choice to support national health and obtain stable investment income; For practitioners, the market is changing with each passing day, and there are many opportunities but fierce competition.

 

To win the hard bones in the field of medicine, we need to unite from policy to market, as well as various therapies and all directions. Various fields with great prospects will gradually merge into one. It should be only a matter of time before China has its own world-class medical center.

 

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Chau, C.H., P.S. Steeg, and W.D. Figg, Antibody-drug conjugates for cancer. Lancet, 2019. 394(10200): p. 793-804.

 

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Wiener CM, Wang Qing, Yin Kanhua. "From gene to society" —— Design logic and implementation process of the new curriculum system of Johns Hopkins University School of Medicine [J]. Fudan Education Forum, 2012 (3): 7. DOI: 10.3969/j.ISSN.1672-0059.2012.03.

 

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2023
BREAKTHROUGH OF THE YEAR. Retrieved December 14, 2023 from
https://www.science.org/content/article/breakthrough-of-the-year-2023

 

* The reference to individual stocks is for reference only and does not constitute investment advice.

 

* The content of this article is provided by the author and does not represent the position of the Earth Knowledge Bureau.

 

Cover: Yitu. com

 

END

 

 

Survivors of Sichuan shipwreck kneel to see their mother-in-law: swimming desperately just to live for their mother.

The whereabouts of his wife and daughter are unknown, and the drowning rescuer Qin Huan and his mother-in-law are crying.

  Restore the "fatal encounter" in Bailong Lake.

  "My son is back." Old Qin stood up and greeted him. This is the second day of the incident.

  Qin Huan was dressed in pajamas, tall, with an intravenous drip in his hand, and was supported by several nurses.

  Qin Huan calm face. Sitting in a courtyard full of relatives, he went straight into the house and went to the third floor without saying hello. Mother-in-law sitting on the sofa, Qin Huan plop down on her knees!

  "Mom, I will be your son in the future." "Mom, actually I don’t want to live. I swam back desperately, just thinking of you. Chunxi is your only daughter. What will you do if she leaves? I swam back desperately to be your son, Mom … … Mom … …”

  Mother-in-law embrace together, grief-stricken, how to pull, Qin Huan also don’t get up.

  The house is full of sadness.

  Fatal encounter

  It was a fatal encounter. Six families met Zhou Piqiang, the ship owner, and then they met the gale together on Bailong Lake. As a result, 18 people traveled, and 14 people are still missing.

  Last Friday, Zhou Piqiang went back to his hometown.

  His hometown is in Group 4, Shunjiang Village, sandui town, facing the dock where the ship stopped. On weekdays, he runs a boat on the other side of the river. His daughter is an adult, but he still has a son to study. The family rented a house in the town and lived in the town, so they seldom go home.

  The old father at home is 76 years old. During the busy farming period, he went home with his wife, found out all the dirty clothes of his old father and washed his father’s quilt sheets. After everything was in order, he and his wife Wang Xingju returned to the rented house in the town.

  Zhou Piqiang told his neighbors that he had spent 5,000 yuan on a new machine. I’ve been going through the formalities. On Friday, the formalities were finally completed. I’m very happy.

  Also on Friday, near the food market in sandui town, because his son Hu Daguo and his daughter-in-law came back with dolls, khufu took a leg of preserved pork from the kitchen and soaked it in hot water, ready to stew it for the next day. Soaked pig’s trotters, around 7 pm, Lao Hu and his wife took a walk in the street with their grandchildren, followed by their son Hu Daguo. As he was walking, Hu Daguo answered a phone call. Hung up the phone, khufu asked his son who called, and his son told him: Qin Huan called, let the past play. "The big country said that it would bring the baby and not go." Old nonsense, then Hu Daguo answered the phone several times, left the child with the old couple of khufu, and passed.

  On Saturday, in the morning, Lao Hu’s wife bought a duck, and his daughter-in-law Yu Min was cooking with her upstairs when someone suddenly shouted. "Say which doll has a birthday, and call for a boat trip to Bailong Lake." Bullshit.

  It’s also Saturday morning. Lao Yang is at the entrance of the living room on the second floor, and his wife is making buns in the kitchen. He heard his son say that Qin Huan called him to take a boat to Bailong Lake. Lao Yang didn’t take it seriously, so he went about his own business.

  … … On Friday, Qin Huan came back from Guangyuan to see her grandmother with his wife and daughter. Just after Children’s Day on June 1st, I met the weekend, and they usually made an appointment with several good friends. The next day, several families were going to Bailong Lake by boat to accompany the dolls.

  Wang Mingxing was also invited, but he went to the appointment alone because of family business.

  In this way, six families and 15 people got on Zhou Piqiang’s boat at Bailong Lake Pier and headed for the upper reaches of the lake.

  Sudden incident

  Around two o’clock in the afternoon, the situation suddenly changed! Dark clouds make sandui town look like evening. Suddenly, there was a thunder in the sky!

  Khufu quickly picked up his mobile phone and called his son. "Where are you?" "We are on the boat and will be back in half an hour." "You put on your life jackets!" "hmm." Hung up the phone, khufu suddenly remembered that he forgot to tell his son and stood on the deck. Hesitated and didn’t call my son again.

  After hanging up the phone for a few minutes, it began to rain, and the strong wind made the trees outside tremble and whine. Khufu ran upstairs, closed the window, put the clothes of the adult doll into the house, and began to call his son again, but it was impossible. I called my daughter-in-law again, but it didn’t work. He ran downstairs, called a car and ran straight to the dock!

  The son’s family went to Bailong Lake, and Lao Yang’s wife was also worried.

  Although her son is 32 years old, he is still a doll in their eyes. Every time Yang Dong goes out, she always keeps in touch for fear that something will happen to him.

  At 2: 05 pm, after the thunder and rain, she dialed her son’s phone.

  "Where have you been?" "I’m on my way home." "Why did you leave?" "I’m sitting on the boat. Why don’t you go?" My son is making fun of my mother over there.

  After nearly an hour, Yang Dong hasn’t come back yet, and she calls her son again. But the phone couldn’t get through, and then I called again, but I still couldn’t get through. I called eight times in a row and couldn’t get through!

  At 3: 21, Lao Yang was playing outside when his wife called: "Yang Dong can’t get through. Go to the dock and have a look!" Lao Yang ran home quickly, got on the bus and ran towards the dock!

  Go ashore alive

  Khufu anxiously rushed to the dock and met Erwa’s brother.

  "Did you see a boat coming back?" "Five ships have gone out, and none has come back yet." The other party said, "I heard there was an accident with a boat."

  Khufu didn’t wait for the other party to finish, so he ran towards the Zhang family’s mouth. Soon he met someone coming up with a doll. He went to see it, not his grandson, and began to walk up again, standing by the river and looking at the water eagerly.

  The water remained calm, as if nothing had happened, only the rescue boat came and went, but there was nothing to do.

  Lao Yang went to the dock and didn’t see anyone. On the way, he saw an ambulance and didn’t stop to ask. Later, I learned that the accident happened in the water near Zhangjiazui, about four kilometers up.

  He later learned that the child who was taken out was a careful doll and had died.

  There are more and more people, and people from the government are here. Later, Lao Yangcai heard that Yang Dong had been sent to the hospital. He quickly turned around and ran to the town hospital. When I arrived at the hospital and saw Yang Dong, I realized that my daughter-in-law Chen Ling and her granddaughter had not got up yet. In less than two months, my granddaughter will celebrate her fifth birthday.

  At three o’clock in the afternoon, the old Qin couple in Qionglai received a phone call from a friend: "Qin Huan’s family has an accident, come back quickly!" Put the phone down, old Qin ran towards Guangyuan. When I went to the hospital in sandui town, my son Qin Huan was already in the hospital, feeling very excited and having an intravenous drip. Probably because of swimming for too long, his leg hurts, and the nurse keeps massaging him. He heard that his daughter-in-law, Pang Chunxi, and his granddaughter were not up yet, and they were being rescued at the scene, and they hurried to the dock, but the traffic control was already on the road, so he had to come back angrily.

  In the hospital, they knew that only Yang Dong, Qin Huan and Wang Mingxing swam ashore alive, and the others were missing.

  The rescue continues, and Lao Hu and Yang, like others, have to wait.

A network anchor responded by lighting a cigarette with "RMB" in the live broadcast: counterfeit money.

  Video screenshot

  Recently, a video of two men lighting cigarettes with a denomination of "RMB" of 100 yuan spread on the Internet, which triggered a heated discussion among netizens. 

  On July 22, Chen Mou, a man who lit a cigarette in the video, told The Paper that the "RMB" he lit was fake money. At first, he only posted the video on WeChat group, but it was threatened after it was uploaded to the network by a willing heart. The man said that he had been reported to the police and has been criticized and educated by the school. 

  On the 22nd, the police on duty at Xingang Road Police Station in Guangzhou told The Paper that the man reported the police more than a month ago and needed to contact the police on duty that day.

  At present, the school where the man is located has no response to this matter.  

  According to a 14-second video posted online, a young man with glasses lit a cigarette in his mouth with a 100-yuan bill, and then the man handed the burning bill to another man wearing a hat next to him to light it. At the end of the picture, the man with glasses is smoking and smiling at the camera. 

  Some netizens pointed out that the man who first lit the RMB in the video was an anchor named "Abstract with Basket" in bilibili. The Paper search found that the anchor had accounts in Sina, Weibo and Tik Tok at the same time, and initially became popular on the Internet as a security guard. 

  On July 22nd, Chen Mou told The Paper that the online video was true, and it was recorded in 2017. The 100 yuan used to light a cigarette in the video was fake money, saying that "it was fun at that time, so it was like this".   

  Chen Mou said that as a student, he usually works as a security guard during the winter and summer vacations. When recording the video, I was a freshman at school. After the video was uploaded to the Internet, I didn’t expect to be threatened by netizens. He said that the behavior of netizens had a certain impact on his personal life, so he reported the case at the Xingang Road Police Station in Guangzhou on June 5, 2019. 

  Chen Mou introduced that he is a native of Shanxi and studied in Guangzhou. The school asked him to delete his video for his own protection. After the incident, he has been criticized and educated by the school. 

  The Paper called the school, but the deadline for publication didn’t get a response. 

  On July 22nd, lawyer Zhang Xinnian, the vice chairman of Beijing Social Organization Legal Mediation Center, told The Paper that according to Articles 27 and 43 of the Regulations on the Administration of RMB, the public security organ should give a warning and impose a fine of less than 10,000 yuan for the intentional destruction of RMB. However, lawyer Zhang Xinnian pointed out that the scope of application of this provision is limited to the currency issued by the People’s Bank of China according to law (that is, real currency). If the man’s burning in the video is indeed "counterfeit money", it is not included in this restriction.

  Zhang Xinnian said that if the burnt RMB is real money or the RMB is counterfeit money, but the man involved conceals the truth and falsely claims that it is real money, the behavior of the man involved in posting the video on the Internet to "show off" and make it widely spread can be regarded as a contempt and provocation against the "RMB" or a suspected violation of public security. If it is investigated by the relevant departments, it can be given a warning, a fine or administrative detention according to the provisions of the Law on Public Security Administration Punishment. On the other hand, if the man involved has informed that it is counterfeit money before lighting the cigarette, it is still controversial whether the act of releasing the video of "counterfeit money lighting the cigarette" is suspected of violating the law and order.

  In addition, due to the limitations of the video content, it is still impossible to judge whether the smoking man is in a "no-smoking area". If the man involved smokes in a "no-smoking area" where smoking is restricted by the local government, he should be punished according to the relevant tobacco control regulations of the local government.

Counting Economy | China’s lithium battery output has increased by over 43%. High-altitude wind power projects are connected to the grid for power generation.

  Cctv newsOn August 3rd, the Ministry of Industry and Information Technology released data. In the first half of this year, China’s lithium battery and photovoltaic industries maintained steady growth.

  The lithium battery industry continued to grow. In the first half of the year, the national lithium battery output exceeded 400GWh, a year-on-year increase of over 43%. The industry-wide revenue of lithium batteries reached 600 billion yuan; The export of lithium battery products increased by 69% year-on-year.

  The output of polysilicon, silicon wafers, batteries and components in the photovoltaic industry chain reached a new high, with a year-on-year increase of over 65%; The total export of photovoltaic products reached US$ 28.92 billion, up 11.6% year-on-year. Look at today’s News Network report.

  △ On August 3, "News Network" reported that the output of lithium batteries in China increased by more than 43% in the first half of the year.

  The revenue of "Top 50 Logistics Enterprises in China" increased by 13.4% year-on-year.

  On August 3rd, China Federation of Logistics and Purchasing released the List of Top 50 Logistics Enterprises in China in 2023. In 2022, the business income of "Top 50 Logistics Enterprises in China" totaled 2,345.6 billion yuan, up 13.4% year-on-year, and the business income of "Top 50 Logistics Enterprises in China" accounted for 18% of the total income of the logistics industry, the highest level in the past years.

  Among the "Top 50 Logistics Enterprises in China", 19 are private enterprises, accounting for a continuous increase. In 2022, the business income of "Top 50 Private Logistics Enterprises" totaled 10,257 yuan, up 18.7% year-on-year.

  China Federation of Logistics and Purchasing announced on the 2nd that in July this year, China’s warehousing index was 52.2%, which was in the expansion range of more than 50% for six consecutive months. The data shows that the production and operation activities of warehousing enterprises are active, the business volume has increased significantly, and enterprises are optimistic about the market prospects.

  The highest altitude wind power project in China has been successfully connected to the grid for power generation.

  On August 3, the highest wind power project in China was successfully connected to the grid in Zhegu Town, Cuomei County, Tibet, which is more than 5,000 meters above sea level. After the project is fully put into production, the annual online electricity consumption will exceed 200 million kWh, which can meet the annual electricity consumption of nearly 140,000 households around; It can save over 60,000 tons of standard coal, reduce carbon dioxide emissions by nearly 173,000 tons and reduce sulfur dioxide emissions by over 20 tons every year.

  In wind power projects, the altitude from 3,500 meters to 5,500 meters is generally referred to as ultra-high altitude area. The wind turbine with a single unit capacity of 3.6 MW connected to the grid is the wind turbine with the largest capacity that has been put into production in ultra-high altitude areas in China.

  The project broke the misunderstanding that "plateau wind energy is weak and has no development value", and at the same time, it designed a fan with special functions such as anti-ultraviolet, anti-lightning, anti-low temperature and anti-icing, which can run stably for a long time in harsh natural environment.

  Xizang Autonomous Region is one of the regions with relatively high wind speed in China. According to preliminary estimation, the technical exploitable capacity of its wind energy resources is about 180 million kilowatts, mainly distributed in high-altitude areas above 4,800 meters.

  △ The picture shows the Cuomei Zhegu Wind Farm in Tibet. (Photo courtesy of Three Gorges Group)

  The scale of nuclear power units under construction in China continues to rank first in the world.

  Recently, Units 5 and 6 of Fujian Ningde Nuclear Power Project, Units 1 and 2 of Shandong Shidaowan Nuclear Power Plant Extension Phase I Project, Units 1 and 2 of Liaoning Xudabao Nuclear Power Project and six nuclear power units were approved by the state. At present, there are 22 nuclear power units under construction in China, and the scale under construction continues to rank first in the world.

  From January to June this year, the cumulative power generation of nuclear power units in operation nationwide was 211.884 billion kWh, accounting for 5.08% of the national cumulative power generation, up by 7.01% over the same period in 2022; The cumulative online electricity consumption was 198.923 billion kWh, up by 7.16% over the same period in 2022.

  Ningde nuclear power project is the first nuclear power plant started and put into operation in Fujian Province. The approved four nuclear power units, including Units 5 and 6 in the second phase of Ningde Nuclear Power Project, will adopt the third-generation nuclear power technology "Hualong No.1" with independent intellectual property rights in China. It is estimated that by the end of the 14th Five-Year Plan, the total number of "Hualong No.1" nuclear power units put into operation in China will exceed 10.

  "Hualong No.1" adopts the world’s highest safety requirements and the latest technical standards. The annual power generation of a single "Hualong No.1" nuclear power unit is nearly 10 billion kWh, which can meet the annual electricity demand of 1 million people. It can reduce the consumption of standard coal by more than 3 million tons and reduce carbon dioxide emissions by more than 8 million tons every year.

  △ The picture shows Fujian Ningde Nuclear Power Plant. (Photo courtesy of CGNPC)

  In the first half of the year, China’s steel output and export volume achieved double growth

  On August 2nd, China Iron and Steel Industry Association released data. In the first half of this year, China’s iron and steel industry operated smoothly, with double growth in output and export volume.

  Specifically, China’s steel output in the first half of the year was 536 million tons, a year-on-year increase of 1.3%; Pig iron output was 452 million tons, up 2.7% year-on-year; Steel output was 677 million tons, up 4.4% year-on-year. In addition, in the first half of the year, China exported 43.58 million tons of steel, a year-on-year increase of 31.3%.

  Over 600 well-known private enterprises visited Shenyang.

  On August 3rd, the All-China Federation of Industry and Commerce organized more than 600 well-known private enterprises to inspect advanced equipment manufacturing, modern agriculture, new energy, metallurgical new materials and other industries in Shenyang, and signed projects with the local government.

  In Liaoning, there are 8,800 small and medium-sized industrial enterprises above designated size, accounting for 97.8% of all industrial enterprises above designated size. The event will have 140 billion yuan of contracted projects in Liaoning, covering new materials, environmental protection and other industries.

[Video] Shanghai Auto Show: A variety of energy-saving and environmentally-friendly new energy vehicles are unveiled.

Enter [China News] > >

    CCTV News (China News): The 2009 Shanghai International Auto Show officially opened to the public on the 21st night. Before and after the opening of this auto show, dozens of domestic and imported models will be listed one after another, and today, with attention to energy conservation and environmental protection, the appearance of various new energy vehicles has also become the focus of this auto show.


    Mini-cars have always been the focus of attention at the auto show because of their cute shape, energy saving and fuel saving. As a mini-hybrid car, the Mercedes-Benz smart sedan that just landed in China on April 8th has attracted many viewers’ attention. BYD, the leader of new energy vehicles in China, brought two hybrid electric vehicles and a pure electric vehicle to this auto show. Exhibitors said that compared with BYD’s new energy vehicles at the Shanghai Auto Show two years ago, the three exhibits this time are more convenient to charge, longer in endurance, higher in fuel economy and lower in cost.


    The new generation of hybrid Buick commercial vehicles exhibited by SAIC is expected to be mass-produced next year. In addition, SAIC has signed an agreement with the Shanghai World Expo Bureau, and its new energy vehicles such as hybrid, pure electric, hydrogen power and supercapacitor will be unveiled at the 2010 Shanghai World Expo.


    In addition to small new energy vehicles, Shaanxi Automobile Group’s energy-saving and environmentally-friendly LNG heavy trucks and compressed natural gas heavy trucks, which represent the future development direction, also appeared at this auto show.


    The reporter noticed that the word hybrid is often mentioned at auto shows, but most hybrid vehicles are still in the concept car stage, and a few have announced mass production plans, and their sales targets are mostly public services such as public transportation and rental. The popularization of new energy vehicles will take some time.

Editor: Li Dan

Xinhua All Media+| What do you think of the economic situation in the first quarter? How to expand domestic demand and strengthen confidence? -The press conference of the National Development and Refo

  Xinhua News Agency, Beijing, April 19th Question: What do you think of the economic situation in the first quarter? How to expand domestic demand and strengthen confidence? — — Press conference of National Development and Reform Commission responds to current economic hotspots.

  Xinhua News Agency reporter Pan Jie

  According to data released by the National Bureau of Statistics on the 18th, China’s GDP increased by 4.5% in the first quarter of this year. How to treat the economic situation in the first quarter? How to expand domestic demand and strengthen confidence? The National Development and Reform Commission held a press conference on the 19th to respond.

  "China has achieved rapid economic recovery"

  Meng Wei, spokesperson of the National Development and Reform Commission, said that China’s economic development achieved a good start in the first quarter. Against the background of the obvious slowdown in global economic growth and high inflation in major economies, China has achieved a rapid economic recovery, laying a solid foundation for completing the goals and tasks of economic and social development throughout the year.

  She said that the characteristics of economic operation in the first quarter were mainly reflected in "expansion of demand, recovery of supply and expected improvement". Domestic demand has gradually expanded, consumption has recovered rapidly, and investment has grown steadily; The recovery of production supply was accelerated, the contact-gathering service industry, which was greatly affected by the epidemic in the early stage, recovered strongly, the producer service industry grew rapidly and the industrial economy grew steadily; Both ends of production and demand continue to expand, and the market is expected to be stable.

  Meng Wei said that the next step will be to firmly grasp the primary task of high-quality development, comprehensively release the potential of domestic demand, promote the sustained recovery of consumption, release the potential of service consumption, effectively stimulate the vitality of private investment, and give play to the guiding role of government investment; Accelerate the construction of a modern industrial system, lay a good battle for key core technologies, and strive to promote industrial upgrading and development; Further deepen reform and opening up, plan and implement a new round of reform of state-owned enterprises, promote the development and growth of private economy, stabilize the basic disk of foreign trade, and attract and utilize foreign capital more vigorously; We will continue to safeguard and improve people’s livelihood, actively stabilize and expand employment, further promote the prevention and control of environmental pollution, and constantly enhance the people’s sense of gain, happiness and security.

  "On the basis of in-depth investigation and research, we will do a solid job in economic operation monitoring, situation analysis and countermeasure research, and timely introduce pragmatic and effective policy measures to consolidate the momentum of expansion and promote the sustained overall improvement of economic operation." She said.

  Take measures to stabilize consumption and promote consumption.

  The data shows that in the first quarter, the contribution rate of final consumption expenditure to economic growth reached 66.6%, which was significantly higher than last year. "The consumer market started well in the first quarter, laying a solid foundation for restoring and expanding consumption throughout the year." Meng Wei said that the driving force for the sustained recovery of consumption needs to be further boosted, and the next step will focus on "sustainability" in four aspects.

  The first is to promote the sustained recovery of consumption. Study and draft policy documents on restoring and expanding consumption, focus on key areas such as stabilizing bulk consumption, improving service consumption and expanding rural consumption, and formulate targeted policy measures according to the needs of different income groups and different consumer goods to promote steady growth of consumption.

  The second is to make great efforts to stabilize automobile consumption. Accelerate the construction of charging piles and urban parking facilities, vigorously promote new energy vehicles to the countryside, and encourage automobile enterprises to develop models that are more suitable for use in county and rural areas. At the same time, accelerate the implementation of the pilot project of comprehensive electrification of vehicles in the public sector.

  The third is to promote the improvement of consumption power. We will optimize the promotion mechanism of employment, income distribution and the virtuous cycle of consumption, strengthen the employment priority policy, increase the income of urban and rural residents, and ensure the supply and price stability of basic consumer goods so that residents can consume and dare to consume.

  The fourth is to further optimize consumption conditions. In view of the institutional mechanism that restricts consumption, we will study and formulate policy documents on creating a safe consumption environment, further improve the standard quality management system, strengthen the construction of consumer credit system, and improve the diversified consumer dispute resolution mechanism and online consumer dispute resolution mechanism, so that ordinary people can gain a strong sense and are willing to spend.

  "Study on reasonably reducing the negative list of foreign investment access"

  On the basis of last year’s high base, China’s utilization of foreign capital has continued to grow this year, and high-tech industries have performed brilliantly. "This fully shows that China is still one of the most attractive investment destinations in the world." Meng Wei said that it will study how to reduce the negative list of foreign investment reasonably, implement the new catalogue of industries to encourage foreign investment and several policies and measures on promoting the expansion of foreign investment with emphasis on manufacturing, and guide foreign investment to invest more in key areas such as advanced manufacturing, modern service industry, high-tech, energy conservation and environmental protection, and key areas such as the central and western regions and the northeast.

  She said that she will continue to play the role of the special class mechanism for major foreign-funded projects and track and solve the problems and difficulties encountered in the project construction process in a timely manner; Improve the management system of development zones, improve supporting policies such as industry, science and technology, and environmental protection, and strengthen the investment attraction function of development zones; Hold a series of international industrial investment cooperation activities to provide a platform for multinational companies to invest in China and attract local investment.

  According to reports, at present, the investment of the first six major foreign-funded projects has exceeded 63 billion US dollars. "We will accelerate the implementation of the first six batches of projects to attract foreign capital inflows. We will improve relevant policies and measures in the field of foreign investment, create a market-oriented, rule-of-law and international first-class business environment, and make greater efforts to attract enterprises from all countries to invest in China. " She said.

  "Let more private capital participate in the construction of major national projects"

  Last year, the National Development and Reform Commission issued a document to increase efforts to support the development of private investment. "Judging from the progress, ‘ Fourteenth Five-Year Plan ’ The task of planning 102 key areas of major projects has been subdivided into specific projects to attract private capital to participate; Strengthen the cooperation and docking of social capital investment and financing. More than 9,000 of the more than 50,000 projects promoted in various places since last year have attracted private capital participation, involving private investment of 2.9 trillion yuan. " Meng Wei said.

  She said that the next step will be to strengthen overall planning and system deployment, establish a mechanism to encourage private capital to participate in major project construction, strengthen information release and guidance, and actively recommend attractive projects to private capital based on the national online approval and supervision platform for investment projects, so that more private capital can participate in the construction of major national projects.

  For major national projects and short-board projects that attract private capital, we will accelerate the preliminary work procedures such as project review and preparation, planning and site selection, land use and sea use, environmental impact assessment, and construction permit, and implement various construction conditions.

  "To implement relevant policies and measures, it is clear that the nature of ownership shall not be used as the selection criteria, and factors such as enterprise scale, registered address and local tax contribution shall not be used as the main bid evaluation conditions. When arranging all kinds of government investment funds, we will treat private capital equally and continue to support major projects in which private capital participates through policy development financial instruments. " Meng Wei said that financial institutions should be promoted to increase credit support for private investment projects according to the principle of marketization. Summarize the good experiences and practices of typical places, typical enterprises and typical projects in time, and replicate and promote them at the national level.

If movie music is a volcano, mr. six is lava.

    Special feature of 1905 film network When Liu Zhenyun’s adaptation of the ending song "Beside" was officially launched on major music platforms today, we once again heard the familiar, sincere and warm voice of that man.                                               

    His name is Zhou Xiaoou, the former lead singer of Zero Band.

Zero Band, which debuted in 1989, is one of the most representative pop rock bands in Chinese music.

 

    Although I have already quit this band, although I have already sung and performed well, Zhou Xiaoou’s song "Love me or not" is still active in KTV’s required repertoire and lingers in the memories of a generation.

 

    This time, the composer who wrote the lyrics for Zhou Xiaoou was the gold medal producer of Chinese rock Depth Charge in the 1990s and across classical and contemporary, rock and pop.

 

    This person is Luan Shu, the former keyboard player and lead singer of Black Panther band, who participated in the production of the Black Panther album that established the position of Panther and Time Walking that established the position of Xu Wei music.

 

A photo of Panther and Beyond, two representatives of mainland and Hong Kong rock bands. The white towel fashion man standing on the left side of cowboy shorts man Dou Wei is Luan Shu.

 

    Later, he was invited by Xiaogang Feng to compose music for films, including the song "It’s better not to meet each other" which quoted Cangyang Jiacuo’s poems.

and

 

    When we talk about Black Panther band, we can’t help but mention Dou Wei, a former soul figure.

 

    From a pioneer of Chinese rock who was able to arrange lyrics and music creation in those years, he has grown into a master of experimental music who is still prolific today. Dou Wei gets more comments like this: Please note that Panther is still singing songs written by Dou Wei in those years to mix money, but Dou Wei has never sung a song written in Panther since he left Panther.

 

    Play a piece of Dou Wei’s piano score, and let’s feel it.

    Compared with the other two "Zhang Chu is dead, He Yong is crazy" in "Magic Rock Three Heroes", Dou Wei is indeed "a fairy".

In 1995, Dou Wei, Zhang Chu and He Yong, together with the Tang Dynasty band, appeared in City Magazine.

 

    With his profound musical attainments, Dou Wei has helped films such as Lu Chuan’s, Cao Baoping’s and Chen Kexin’s score, among which he won the Golden Horse Award for Best Original Music.

Dou Wei once sang "Wandering the Jianghu", which was called "Rock Buddhist Sutra" by Chen Kexin.

    After talking about the hermit, how can you forget that the music scene is "half of the country"?

 

    Although Wang Old Master Q is making headlines in the entertainment circle all day today, fifteen years ago, he wrote all the movie music for the film that the sixth generation director Wang Xiaoshuai won the Silver Bear Award at the Berlin Film Festival.

Gao YuanyuanStarring in a youth movieSeventeen-year-old bike

    However, this dream tutor has also been ridiculed for "Without Wang Feng, the mainland music scene would be lost by half", and the most famous one is undoubtedly the song title of Zheng Jun, a long-time friend.

    Speaking of Zheng Jun, he was drop-dead gorgeous among Chinese rock talents.

 

Gao XiaosongIt has been said that when Zheng Jun was young, he was hot and talented, and he was very prominent in the rock circle where he looked generally obscene.

 

    At the end of 1999, Zheng Jun sang the theme song "Why Flowers Are So Red" for a film directed by Gao Xiaosong, and worked continuously for 14 hours in the recording studio from arranging music to playing guitar to recording and singing.

 

ParticipatinghackberryandZhou XunLater stories, you know.

    This year, Zheng Jun sang the theme song "Love" of the self-directed animated film.

    Finally, of course, Cui Jian, the "godfather of rock and roll", made the finale.

 

    This ultimate mr. six, recognized by People’s Daily and the United Nations, is an idol of Wang Shuo, Xiaogang Feng, Jiang Wen and others, and is also called "China’s great music poet" by Yu Guangzhong.

 

Cui Jian and his red five-star hat have become a symbol.

 

    In 2014, Cui Jian wrote the song "Love between Fish and Birds" for his first film.

    I know I shouldn’t think of this song at this point.

    But after talking about it, I found that for so many years, most of these Chinese rock and roll have never stopped to contribute to China movies.

 

    Talking about this, I found that mr. six, who seems to be arrogant, often becomes an unknown person behind the scenes.

 

    When we talk about this, we find that what we think of as rebellion is actually the most real warmth.

 

    Therefore, when Zhou Xiaoou’s "memory killing" voice meets the movie this time, I hope everyone will go to the cinema to support the movie, especially after watching it, don’t leave in a hurry, just sit and listen to his songs before leaving.

Maoyan Entertainment’s net profit has increased by more than 7 times, and the movie box office has reached a new high.

[Maoyan Entertainment’s net profit increased by more than 7 times last year, and the stock price of Hong Kong stocks rose by more than 5%. Institutions are optimistic about the record box office this year]

Maoyan Entertainment’s share price is strong today. At the close, the increase reached 5.39% to HK$ 10.36, with a turnover of HK$ 42,886,900.

Maoyan Entertainment will release its annual results on March 21st. Yingxi announcement shows that the company expects its revenue in 2023 to be 4.7-4. 8 billion yuan, up by about 102.6% to 106.9% year-on-year; The net profit of returning to the mother was 880 to 930 million yuan, a year-on-year increase of 739.7% to 787.4%. CICC believes that the performance forecast exceeded expectations, mainly due to the strong performance of Chinese New Year movies, proper control of management expenses and adjustment of the forecast income tax rate.

According to the data of Lighthouse Professional Edition, as of March 10th, the box office in 2024 (including pre-sale) has exceeded 15 billion yuan. Guosen Securities (002736) predicts that the box office of China movie (600977) is expected to exceed the level of 64.2 billion yuan in 2019 and hit a new record high, driven by the supply cycle of domestic movies and Hollywood movies. The high operating leverage characteristics make the broadcast channel expect to usher in a better profit release period.


9 am! AFC executives announced major news: Congratulations to China Football! The fans cheered in unison

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Title: Rekindle the Blood: The Road to the Revitalization of China Football and the Asian Charm of Badminton When the hope of China Football is far away in the international arena, a sudden news is like a dawn, which breaks the dawn and illuminates the hope of China Football Revitalization. This is not only an exciting news, but also a confirmation of the deep belief of hundreds of millions of China fans. Let’s open a new chapter in China football and Asian badminton, which is a story about perseverance and continuous progress.

1. China Football: Preface to Challenge, Reform and Revitalization In the history of China football, we witnessed many tragic scenes. Our players wore battle shirts and sweated, and countless setbacks failed to break their progress. But this time, the meeting between AFC President Salman and China Football Association President Song Kai was like a long-lost rain after a drought, which injected vitality into China football.

President Salman’s full support is not an empty slogan, it indicates the recognition and expectation of China’s football reform in international football. This is not only an opportunity, but also an important task, a commitment to history and to hundreds of millions of China fans.

Second, the expectation of fans and the cultural connotation of China football. The spirit of China football is far more than a 90-minute game. It is related to a culture, a kind of perseverance and unity and cooperation deeply rooted in the bone marrow of the Chinese nation. Our fans expect not only the victory of the game, but also the embodiment and inheritance of this spirit.

Third, the witness of history: China’s tenacious spirit. Every struggle in adversity and every competition is the best interpretation of China’s football spirit. This spirit is our precious wealth. It tells us that no matter how powerful our opponent is, we will never give up.

Fourth, unite as one: the unchangeable principle of China football. Within the China football team, unite as one is an eternal theme. This unity can help us overcome difficulties in international competitions and create miracles in domestic leagues.

5. Enterprising mentality: The transformation and breakthrough of China football. From the introduction of coaches to the training of players, China football has been constantly trying and reforming. This enterprising mentality is our best weapon in the face of international competition.

6. Badminton in the Asian Games: A venue for displaying Asian charm. Let’s take a look at badminton events in the Asian Games. This is not only a sports competition, it is an exchange of cultures and skills of Asian countries, and it is also a concentrated display of badminton charm.

Vii. The Beauty of Competition: A Review of Badminton Events in the Last Asian Games. In the badminton events in the last Asian Games, the outstanding performance of players from various countries showed the world the level of Asian badminton. Every swing, every leap tells the dream and sweat of Asian badminton players.

Badminton in China: The embodiment of honor and team spirit. Every minute and second of the China team on the court is telling honor and responsibility. Our athletes make friends with the ball and promote peace with the game, which embodies the team spirit and the principle of friendship first in badminton.

Cultural exchange of badminton events in the Asian Games The Asian Games is not only a sports feast, but also a bridge of culture and friendship. In badminton competitions, we saw mutual respect and learning in different cultural backgrounds.

X. Looking to the Future: A New Journey of Asian Badminton With the continuous development of Asian badminton, we look forward to seeing more Asian faces on the international stage in the future, and we also hope that this sport will continue to spread its unique charm.

From China football to Asian badminton, we see not only the fierceness and beauty of sports, but also the depth and breadth of culture behind sports. Let’s hope that in the future, China football and Asian badminton will shine on the international stage, bringing more excitement and encouragement to sports fans all over the world.

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